Virus incl. Viroids & Prions
SARS-CoV2 (attenuated, vaccination strains)
Strain/Type
sCPD9 & sCPD9-ΔFCS
Source/Company
Vetenerian Institute FUB, Jakob Trimpert & Benedikt Kaufer, Kontakt Dusan Kunec (Dusan.Kunec@fu-berlin.de)
Usage Regulation and Limitations
- for research purposes only
- only for AG Haag, contact of Katharina Achazi required before use
- only testing of new therapeutics
- no vaccine development
How to cite
cite Trimpert J et al. (2021). Cell Rep. 36(5):109493.
Host tropism
human, bat, etc.
Route of Transmission
aerogen (inhalation), air-borne
Characteristics e.g. sensitizing or toxic effects, replication deficiant, not infectious, attenuated, inactivated (upload relevant documents)
causes infection
Approved as biological safety measure if taken as recipient organism for genetic engineering?
no
Genetically modified (GenTSV)
yes, S2 (see here: 2024-XX-XX S2 Arbeit 92/14-4: attenuated SARS-CoV2 sCPD9 & sCPD9-ΔFCS)
Risk group (BioStoffV)
RG2
Risk assessment
Operation instructions (mandatory for RG2 and higher)According to ZKBS (888-12-4b LAGeSo-Änderung Genehmigung v. 12.5.22.pdf) and LaGeSo (888-12-4b ZKBS-Stellungnahme v. 5.4.22.pdf)
For detailed risk assessment (Gefährdungsbeurteilung), operating instructions & related permissions see: GMOs & Pathogens
Operation instructions (mandatory for RG2 and higher)
For detailed risk assessment (Gefährdungsbeurteilung), operating instructions & related permissions see: GMOs & Pathogens
Occupational health care (according to ArbMedVV)
yes
Storage location of aliquots in the Biolab (just click Bearbeiten in the right corner of the header to add or change information in the table and use the menue in the left header to e.g. add a row)
| source | virus strain | freezing date | virus amount per vial | stock was produced on | no. of aliquots | belongs to (full name) | rack/box in N2 tank or -80°C freezer and location (room, address) | comments |
|---|---|---|---|---|---|---|---|---|
SCPD9 | 2024.10.18 | not determined | VeroE6 | 6 | Chuanxiong Nie | C-2-31， -80oC Π （raum 114, Altensteinstr 23a, 14195 Berlin） | labeled as SCPD9_4241 | |
| SCPD9_ΔFCS | 2024.10.18 | not determined | VeroE6 | 6 | Chuanxiong Nie | C-2-31， -80oC Π （raum 114, Altensteinstr 23a, 14195 Berlin） | labeled as SCPD9_4636 |
Background
Groenke N et al. (2020). Cell Rep. 31(4):107586.
Trimpert J et al. (2021). Cell Rep. 36(5):109493.
Trimpert J et al. (2021). Sci Adv. 7(49):eabk0172.
Trimpert J et al. (2020). Cell Rep. 8;33(10):108488.
Jackson CB et al. (2021). Biochem Biophys Res Commun. 538:108-115.
Volz E et al. (2021). Cell. 184(1):64-75.e11.
Cultivation and freezing protocols
Data sheets, inactivation cetificate, further information
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