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Kommentar: Migrated to Confluence 5.3

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Synonyms

Gene

mRNA

Protein

Diseases

Crystal Structures

BMP2B BMP2b
BMP2b1 BMP2B1
ZYME

Entrez:
Bmp4 (human)
empty
empty
Bmp4(mouse)

NCBI:
NM_001202 (human)
NM_130850 (human)
NM_130851 (human)
NM_007554 (mouse)

NCBI:
NP_001193 (human)
NP_570911 (human)
NP_570912 (human)
NP_031580 (mouse)

UniProtKB/Swiss-Prot:
P12644 (human)
P21274 (mouse)

OMIM:
*112262

FOP
cleft lip
cleft palate



RCSB PDB:
%

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Processing

The activity and signaling range of mature BMP-4 is regulated by sequential cleavage at two sites within the prodomain of the precursor (Ref).

Cleavages within the prodomain direct intracellular trafficking and degradation of mature bone morphogenetic protein-4 (Ref).

Targeting of bone morphogenetic protein growth factor complexes to fibrillin (Ref).

Expression

Developmental stages, tissues, etc.

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Further reading:

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