Seitenhistorie

Virus

Feline Coronavirus (FeCoV )

Felines Coronavirus (FeCoV )Alphacoronavirus 1 infraspecies Feline infectious peritonitis virus
Feline infectious peritonitis virus （FIPV）

Alphacoronavirus 1 Infraspezies Felines Infektiöses Peritonitis-Virus
Virus der Felinen Infektiösen PeritonitisCoronavirus

Strain/Type

Feline coronavirus (ATCC VR-989, WSU 79-1683) 

Host tropism

catscaoV,

Route of Transmission

The virus is shed in feces, and cats become infected by ingesting or inhaling the virus, usually by sharing cat litter trays, or by the use of contaminated litter scoops or brushes transmitting infected microscopic cat litter particles to uninfected kittens and cats.

FCoV can also be transmitted through different bodily fluids. The virus is easily spread through direct contact between cats. The most common form of spreading is through saliva, as most multiple cat homes share food and water dishes.

Another major form of spreading is grooming or fighting. When an infected cat grooms a healthy cat, they leave their contaminated saliva on the fur. Later, when the healthy cat goes to groom themselves, they ingest the contaminated saliva and then become infected.

FCoV is caught by inadvertently swallowing the virus, through contact with other cats, litter trays or soil where other cats have toileted. Exposure to faeces in the litter tray is the most common means of transmission

Characteristics e.g. sensitizing or toxic effects, replication deficiant, not infectious, attenuated, inactivated (upload relevant documents)

Note t2:

Owing to the pathogenicity for vertebrates, safety measures may be necessary under animal disease legislation which, analogous to the safety measures of protection level 2, minimise the escape of prokaryotes into the external environment or other working areas. 

Approved as biological safety measure if taken as recipient organism for genetic engineering?

Genetically modified (GenTSV)

Risk group (BioStoffV)

1

Risk assessment

Risk accessment based on TRBA (Technical Rule for Biological Agents) 462 "Classification of viruses into risk groups": https://www.baua.de/DE/Angebote/Rechtstexte-und-Technische-Regeln/Regelwerk/TRBA/TRBA-462.html

Operation instructions (mandatory for RG2 and higher)

https://bioagent.dguv.de/data?name=830366&lang=en830365

Occupational health care (according to ArbMedVV)

The consumption and storage of food and alcohol/tobacco in the protection level area is forbidden.
The hands are to be thoroughly cleaned and treated according to the hand protection plan following completion of the activities or contamination processesIn the case of activities with the biological agent no health care is required. An indication on restrictions for immunosuppressed workers should be made.

Storage location of aliquots in the Biolab (just click Bearbeiten in the right corner of the header to add or change information in the table and use the menue in the left header to e.g. add a row)

Background

Cultivation and freezing protocols

Data sheets, inactivation cetificate, further information