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Schlüssel

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Virus

RS-Virus, Respiratory syncytial virus, HRSV-A2, -B1, -S2

Strain/Type

Genus: Pneumovirus

Host tropism

Humans; however, various animal species can be experimentally infected with RSV including cotton rats, mice, ferrets, guinea pigs, hamsters, marmosets, lambs, and nonhuman primates.

Route of Transmission

RSV is most likely transmitted through direct contact with infectious secretions (via fomites) and/or large-particle aerosols; however, close contact with infected individuals, or significant exposure of nasal or conjunctival mucosa with contaminated hands is required for transmission. Transmission via small-particle aerosols is less likely.

Zoonosis (transmission between animals and humans): No

Characteristics e.g. sensitizing or toxic effects, replication deficiant, not infectious, attenuated, inactivated (upload relevant documents)

Human-pathogenic (causes diseases in humans).

Approved as biological safety measure if taken as recipient organism for genetic engineering?

Genetically modified (GenTSV)

Risk group (BioStoffV)

2

Risk assessment

Risk accessment based on TRBA (Technical Rule for Biological Agents) 462 "Classification of viruses into risk groups": https://www.baua.de/DE/Angebote/Rechtstexte-und-Technische-Regeln/Regelwerk/TRBA/TRBA-462.html

Operation instructions (mandatory for RG2 and higher)

https://biostoffe.dguv.de/data?name=830764&lang=en

View file
nameHumanes Respiratorisches Synzytial-Virus_Biostoffdokument-830764_en.pdf
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View file
nameHumanes Respiratorisches Synzytial-Virus_Biostoffdokument-830764.pdf
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Occupational health care (according to ArbMedVV)

Optional health care:
In the case of tasks specifically involving contact and tasks involving incidental contact with biological agents classed as Risk Group 2 under the Biological Agents Ordinance (Biostoffverordnung, BioStoffV) or which involve a comparable risk, the employer must offer an optional health care. This does not apply when on account of the risk assessment and on account of the protective measures taken it can be assumed that there is no risk of infection.
An optional health care must also be offered if as a result of the exposure to biological agents
- a serious infectious illness is to be expected and post-exposure prophylatic measures are possible, or
- an infection has resulted.

Vaccination:

None available.

Storage location of aliquots in the Biolab (just click Bearbeiten in the right corner of the header to add or change information in the table and use the menue in the left header to e.g. add a row)

sourcevirus strainfreezing datevirus amount per vialstock was produced onno. of aliquotsbelongs to
(full name)

rack/box in N2 tank or -80°C freezer and  location (room, address)


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Background

Cultivation and freezing protocols

Data sheets, inactivation cetificate, further information