Virus
Vesicular stomatitis Indiana virus
Vesicular stomatitis virus
VS virus
Stomatitis vesicularis virus
VSIV
Strain/Type
Genus: Vesiculovirus
Host tropism
Humans (except for Maraba and Cocal viruses), horses, cattle, pigs, mules, sand flies, grasshoppers, and rodents.Route of Transmission
Bite of an infected sand fly; by direct contact with abrasions on the skin; by contact with infected domestic animals; or by inhaling aerosols via the nasopharyngeal route. The virus has also been transmitted via accidental autoinoculation or inhalation of aerosols in a laboratory setting.
Yes, humans can contract VSV through direct contact with infected animals, or indirectly through the bite of an infected fly
Characteristics e.g. sensitizing or toxic effects, replication deficiant, not infectious, attenuated, inactivated (upload relevant documents)
Note Z:
The viruses labelled "Z" in TRBA 462 include the zoonotic agents specified in EU Directive 2003/99/EC, and further viruses falling under item B.4 Annex I of EU Directive 2003/99/EC, but not specifically referred to there. These labels are derived from leaflet B 004/2011 “Safe biotechnology – classification of biological agents: viruses” of the German Social Accident Insurance Institution for the raw materials and chemical industry (BG RCI); BGI 631.
Zoonotic agents include all viruses, bacteria, fungi, parasites and other biological entities capable of causing zoonosis.
Zoonosis is any disease and/or infection which is naturally transmissible directly or indirectly between animals and humans.
Footnote z:
The conditions of protection level 3 must be observed during experiments on equids, bovines and pigs. Infected small laboratory animals must be kept insect free.
Approved as biological safety measure if taken as recipient organism for genetic engineering?
Genetically modified (GenTSV)
Risk group (BioStoffV)
2
Risk assessment
Risk accessment based on TRBA (Technical Rule for Biological Agents) 462 "Classification of viruses into risk groups": https://www.baua.de/DE/Angebote/Rechtstexte-und-Technische-Regeln/Regelwerk/TRBA/TRBA-462.html
Operation instructions (mandatory for RG2 and higher)
https://biostoffe.dguv.de/data?name=831148&lang=en
Occupational health care (according to ArbMedVV)
Optional health care:
In the case of tasks specifically involving contact and tasks involving incidental contact with biological agents classed as Risk Group 2 under the Biological Agents Ordinance (Biostoffverordnung, BioStoffV) or which involve a comparable risk, the employer must offer an optional health care. This does not apply when on account of the risk assessment and on account of the protective measures taken it can be assumed that there is no risk of infection.
An optional health care must also be offered if as a result of the exposure to biological agents
- a serious infectious illness is to be expected and post-exposure prophylatic measures are possible, or
- an infection has resulted.
Storage location of aliquots in the Biolab (just click Bearbeiten in the right corner of the header to add or change information in the table and use the menue in the left header to e.g. add a row)
| source | virus strain | freezing date | virus amount per vial | stock was produced on | no. of aliquots | belongs to (full name) | rack/box in N2 tank or -80°C freezer and location (room, address) | comments |
|---|---|---|---|---|---|---|---|---|
