Klebsiella pneumoniae RG 2

Bacteria

klebsiella pneumoniae

Strain/Type

clinical isolate

Host tropism

human

Route of Transmission

Characteristics e.g. sensitizing or toxic effects, resistance to antibiotics

Pathogenicity

Facultative human-pathogenic (it does not necessarily cause diseases in humans).

Facultative animal-pathogenic (it does not necessarily cause diseases in animals).

Resistances

Klebsiella pneumoniae exhibits environmental resistance, which allows it to survive for longer periods on vegetables, in refrigerated foods, on surfaces, on the skin and in other locations. However, the ability of Klebsiella pneumoniae to pick up resistances to antibiotics is of greater significance. Apart from its natural resistance to ampicillin and carbenicillin, resistances to many other penicillins and to cephalosporins may be acquired with the aid of various expanded spectrum betalactamases (ESBL). The circumstance that Klebsiella pneumoniae may also form resistances to carbapenems with the aid of special carbapenemases is a threat. If an appropriately equipped strain triggers an infection, there are scarcely any options available for an intervention with antibiotics.

Approved as biological safety measure if taken as recipient organism for genetic engineering?

Genetically modified (GenTSV)

no

Risk group (BioStoffV)

RG 2

Risk assessment

Operation instructions (mandatory for RG2 and higher)

Occupational health care (according to ArbMedVV)

Storage location of aliquots in the Biolab (just click Bearbeiten in the right corner of the header to add or change information in the table and use the menue in the left header to e.g. add a row)

Background

Cultivation and freezing protocols

Data sheets, further information