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Bone morphogenetic protein 4 (BMP4)

Synonyms

Gene

mRNA

Protein

Diseases

Crystal Structures

BMP2B
BMP2B1
ZYME

Entrez:
Bmp4 (human)
empty
empty
Bmp4(mouse)

NCBI:
NM_001202 (human)
NM_130850 (human)
NM_130851 (human)
NM_007554 (mouse)

NCBI:
NP_001193 (human)
NP_570911 (human)
NP_570912 (human)
NP_031580 (mouse)

UniProtKB/Swiss-Prot:
P12644 (human)
P21274 (mouse)

OMIM:
*112262

FOP
cleft lip
cleft palate



RCSB PDB:
%


Processing

The activity and signaling range of mature BMP-4 is regulated by sequential cleavage at two sites within the prodomain of the precursor (Ref).

Targeting of bone morphogenetic protein growth factor complexes to fibrillin (Ref).

Expression

Developmental stages, tissues, etc.

Knockouts

Types of knockouts, phenotypes, etc.


Further reading:

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