Bacteria

Salmonella enterica (choleraesuis) subsp. enterica

Strain/Type

Salmonella enterica (choleraesuis) subsp. enterica

Host tropism

Bacteria of the Salmonella genus are widespread in nature. They can be detected in many cold and warm-blooded animals across the globe. In numerous countries today they are the most important bacterial diarrhoea-causing pathogens in man.

Route of Transmission

Salmonella bacteria are widely distributed in domestic and wild animals. They are prevalent in food animals such as poultry, pigs, and cattle; and in pets, including cats, dogs, birds, and reptiles such as turtles.

Salmonella can pass through the entire food chain from animal feed, primary production, and all the way to households or food-service establishments and institutions.

Salmonellosis in humans is generally contracted through the consumption of contaminated food of animal origin (mainly eggs, meat, poultry, and milk), although other foods, including green vegetables contaminated by manure, have been implicated in its transmission.

Person-to-person transmission can also occur through the faecal-oral route.

Human cases also occur where individuals have contact with infected animals, including pets. These infected animals often do not show signs of disease.

Characteristics e.g. sensitizing or toxic effects, resistance to antibiotics

Note Z:
Bacteria bearing the "Z" identifying tag in the present TRBA encompass the zoonotic pathogens named in Directive 2003/99/EC and other bacteria falling under B.4 Annex I of Directive 2003/99/EC but not specifically named there. These identifying tags originate from the BG informative document "Safe biotechnology – Classification of biological agents: prokaryotes (bacteria and archaea)" of the German Social Accident Insurance Institution for the raw materials and chemical industry (BG RCI).

Zoonotic pathogens are all viruses, bacteria, fungi, parasites or other biological units capable of causing zoonoses.
Zoonoses encompass all diseases and/or all infections which can be transmitted by natural routes directly or indirectly between animals and humans.
    
Footnote 1:
Nomenclature according to Popoff, M.Y. & Leminor, L.E.: Genus XXXIII. Salmonella Lignières 1900, 389AL, pp.764-799, in: Garrity, G.M. (Editor-in-chief), Brenner, D.J., Krieg, N. R., Staley, J. T. (Editors of Vol. 2): Bergey’s Manual of Systematic Bacteriology, 2nd Edition, Vol. 2 The Proteobacteria, Part B The Gammaproteobacteria. Springer, Dordrecht-Heidelberg-London-New York 2005.
Note: Footnote 1 in the new version (currently in preparation) of the "Prokaryotes" leaflet and of the TRBA 466.
Footnote 2:
Except Salmonella Typhi and Salmonella Paratyphi A, B, C.

Approved as biological safety measure if taken as recipient organism for genetic engineering?

Genetically modified (GenTSV)

Risk group (BioStoffV)

2

Risk assessment

Risk accessment based on TRBA (Technical Rule for Biological Agents) 466 "Classification of prokaryotes (bacteria and archaea) into risk groups": https://www.baua.de/DE/Angebote/Rechtstexte-und-Technische-Regeln/Regelwerk/TRBA/TRBA-466.html

Operation instructions (mandatory for RG2 and higher)

https://bioagent.dguv.de/data?name=825888

Occupational health care (according to ArbMedVV)

Optional health care:
In the case of tasks specifically involving contact and tasks involving incidental contact with biological agents classed as Risk Group 2 under the Biological Agents Ordinance (Biostoffverordnung, BioStoffV) or which involve a comparable risk, the employer must offer an optional health care. This does not apply when on account of the risk assessment and on account of the protective measures taken it can be assumed that there is no risk of infection.
An optional health care must also be offered if as a result of the exposure to biological agents
- a serious infectious illness is to be expected and post-exposure prophylatic measures are possible, or
- an infection has resulted.

Storage location of aliquots in the Biolab (just click Bearbeiten in the right corner of the header to add or change information in the table and use the menue in the left header to e.g. add a row)

sourcebacterial strainfreezing dateamount of bacteria  per vialstock was produced onno. of aliquotsbelongs to
(full name)

rack/box in N2 tank or -80°C freezer and  location (room, address)


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Background

We have permission to work with this pathogen but it is currently not stored in our facilities. Contact Tatyana Povolotsky if you are interested in working with this organism.

Cultivation and freezing protocols

Data sheets, further information

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