Virus
Herpes simplex virus typ 1
Herpes simplex-Virus Typ 1
HHV-1
Strain/Type
Genus: Simplexvirus
Host tropism
Humans.
Zoonosis (transmission between animals and humans): Yes
Primates as well as rabbits and rodents can be infected, but do not represent a natural reservoir for human herpes viruses.
Route of Transmission
Transmission takes place percutaneously (through the skin).
Transmission takes place orally (by ingestion).
Characteristics e.g. sensitizing or toxic effects, replication deficiant, not infectious, attenuated, inactivated (upload relevant documents)
Human-pathogenic (causes diseases in humans).
Approved as biological safety measure if taken as recipient organism for genetic engineering?
Genetically modified (GenTSV)
Risk group (BioStoffV)
2
Risk assessment
Risk accessment based on TRBA (Technical Rule for Biological Agents) 462 "Classification of viruses into risk groups": https://www.baua.de/DE/Angebote/Rechtstexte-und-Technische-Regeln/Regelwerk/TRBA/TRBA-462.html
Operation instructions (mandatory for RG2 and higher)
https://biostoffe.dguv.de/data?name=830562&lang=en
Occupational health care (according to ArbMedVV)
Optional health care:
In the case of tasks specifically involving contact and tasks involving incidental contact with biological agents classed as Risk Group 2 under the Biological Agents Ordinance (Biostoffverordnung, BioStoffV) or which involve a comparable risk, the employer must offer an optional health care. This does not apply when on account of the risk assessment and on account of the protective measures taken it can be assumed that there is no risk of infection.
An optional health care must also be offered if as a result of the exposure to biological agents
- a serious infectious illness is to be expected and post-exposure prophylatic measures are possible, or
- an infection has resulted.
Vaccination:
None available.
Storage location of aliquots in the Biolab (just click Bearbeiten in the right corner of the header to add or change information in the table and use the menue in the left header to e.g. add a row)
| source | virus strain | freezing date | virus amount per vial | stock was produced on | no. of aliquots | belongs to (full name) | rack/box in N2 tank or -80°C freezer and location (room, address) | comments |
|---|---|---|---|---|---|---|---|---|
| FU-Institute of Virology | HSV-1 | 2023.01.23 | 2.4 x 10^7 PFU/mL, 1mL | Vero | 9 | Ranen Etouki/Chuanxiong Nie | C21, -80oC freezer, Π (SupraFab, Altensteinstraße 23a, 114.1) | discarded on 21.04.2023 |
| FU-Insitute of Virology | HSV-1 | 2023.01.23 | 7.6 x 10^6 PFU/mL, 1mL | Vero | 9 | Yanping Long/Chuanxiong Nie | C21, -80oC freezer, Π (SupraFab, Altensteinstraße 23a, 114.1) | discarded on 21.04.2023 |
| FU-Institute of Virology | HSV-1 | 2023.04.27 | 10^7 PFU/mL, 1mL | Vero | 9 | Chuanxiong Nie | C21, -80oC freezer, Π (SupraFab, Altensteinstraße 23a, 114.1) | |
| FU-Institute of Virology | HSV-1 | 2023.05.05 | 10^8 PFU/mL, 1mL | Vero | 9 | Chuanxiong Nie | C21, -80oC freezer, Π (SupraFab, Altensteinstraße 23a, 114.1) |
